United States
Africa & Oceania
Cheapest fare
$138
Fastest
2h 14m
Direct from
$138
Dates tracked
6
Cheapest fare
$138
Thu, Jan 14 · Direct · 2h 14m · American Airlines
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October 2026
Price alert
Cheapest day to fly
Tuesday
Averages $281, vs $515 on Wednesdays.
Work-hours calculator
This flight to Santiago costs you 9h 12m of work.
Same money as
2
SUV fuel tanks
8
large pizzas
11
cinema tickets
23
fancy coffees
American Airlines
from $138 · 6 dates
Destination guide

About Santiago
Santiago de los Caballeros ("Saint James of the Knights"), often shortened to Santiago, is the second-largest city in the Dominican Republic and the fourth-largest city in the Caribbean by population. It is the capital of Santiago Province and the largest major metropolis in the Cibao region of the country. Santiago is the largest Caribbean city that is not a capital city, and the largest non-coastal metropolis in the Caribbean islands.
Text from Wikipedia — Santiago de los Caballeros, licensed CC BY-SA 4.0.
All dates
| Departs | Return | Airline | Stops | Price |
|---|---|---|---|---|
| Wed, Oct 28 | Sun, Nov 1 | American Airlines | 1 stop | $515 |
| Mon, Nov 2 | Mon, Nov 23 | American Airlines | Direct | $444 |
| Tue, Nov 10 | Mon, Nov 16 | American Airlines | Direct | $281 |
| Thu, Dec 3 | Wed, Dec 9 | American Airlines | Direct | $304 |
| Mon, Jan 11 | Mon, Feb 1 | American Airlines |
Also cheap
FAQ
The cheapest fare we see right now is $138 one way on Thu, Jan 14 with American Airlines.
Yes — direct fares start from $138.
The fastest itinerary we track takes about 2h 14m door to door.
Tuesday departures are the cheapest on average right now, Wednesday the most expensive.
December 2026
Prices in USD. Click a day to see that fare on our booking partner (affiliate link).
| Direct |
| $254 |
| Thu, Jan 14 | One way | American Airlines | Direct | $138 |
Dominican Republic
Thu, Jan 28 · Direct · 2h 20m · Arajet
Dominican Republic
Mon, Jan 11 · 1 stop · 5h 19m · American Airlines